PKD-IN-1 dihydrochloride

• CAT Number: I041805
• CAS Number: 2308510-39-4
• Molecular Formula: C18H21Cl3N4O
• Molecular Weight: 415.74
• Purity: ≥95%
• Synonyms: 2-[4-[[(2R)-2-aminobutyl]amino]quinazolin-2-yl]-4-chlorophenol;dihydrochloride
• InChI: InChI=1S/C18H19ClN4O.2ClH/c1-2-12(20)10-21-17-13-5-3-4-6-15(13)22-18(23-17)14-9-11(19)7-8-16(14)24;;/h3-9,12,24H,2,10,20H2,1H3,(H,21,22,23);2*1H/t12-;;/m1../s1
• InChIKey: ASWGDWBLOLWOED-CURYUGHLSA-N
• SMILES: CCC(CNC1=NC(=NC2=CC=CC=C21)C3=C(C=CC(=C3)Cl)O)N.Cl.Cl

PKD-IN-1 dihydrochloride (compound 32), an aminoethylamino-aryl (AEAA) compound, acts as PKD-1 inhibitor. PKD-IN-1 can be used for protein kinase D (PKD)-mediated diseases research[1].

Reference

[1]. RT Michael, et al. Aminoethylamino-aryl (AEAA) compounds as PKD inhibitors and their preparation, pharmaceutical compositions and use in the treatment of PKD-mediated diseases: World Intellectual Property Organization, WO2007125331. 2007-11-08.