PKM2 activator 5

For research use only. Not for therapeutic Use.

  • CAT Number: I042629
  • CAS Number: 796092-26-7
  • Molecular Formula: C18H19FN2O6S2
  • Molecular Weight: 442.48
  • Purity: ≥95%
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PKM2 activator 5(Cat No.:I042629)is a small molecule designed to selectively activate pyruvate kinase M2 (PKM2), an enzyme that plays a critical role in the regulation of glycolysis, energy production, and cellular metabolism. PKM2 is often dysregulated in cancer cells, where it contributes to the Warburg effect, allowing tumor cells to maintain high rates of glycolysis even in the presence of oxygen. By activating PKM2, PKM2 activator 5 aims to restore normal metabolic functions and inhibit cancer cell proliferation. It is being explored as a potential therapeutic agent for cancer treatment, particularly in metabolic reprogramming strategies.


CAS Number 796092-26-7
Synonyms

1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-(3-fluorophenyl)sulfonylpiperazine

Molecular Formula C18H19FN2O6S2
Purity ≥95%
IUPAC Name 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-(3-fluorophenyl)sulfonylpiperazine
InChI InChI=1S/C18H19FN2O6S2/c19-14-2-1-3-15(12-14)28(22,23)20-6-8-21(9-7-20)29(24,25)16-4-5-17-18(13-16)27-11-10-26-17/h1-5,12-13H,6-11H2
InChIKey SOEFEUAERZUSNF-UHFFFAOYSA-N
SMILES C1CN(CCN1S(=O)(=O)C2=CC3=C(C=C2)OCCO3)S(=O)(=O)C4=CC=CC(=C4)F

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