PKN3 inhibitor compound 16

• CAT Number: I047688
• CAS Number: 2361545-75-5
• Molecular Formula: C18H17IN2O3
• Molecular Weight: 436.24
• Purity: ≥95%
• IUPAC Name: 7-iodo-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
• InChI: InChI=1S/C18H17IN2O3/c1-22-16-9-12(10-17(23-2)18(16)24-3)21-14-6-7-20-15-8-11(19)4-5-13(14)15/h4-10H,1-3H3,(H,20,21)
• SMILES: COC1=CC(=CC(=C1OC)OC)NC2=C3C=CC(=CC3=NC=C2)I

PKN3 inhibitor compound 16 is a potent, cell-active protein kinase novel 3 (PKN3) inhibitor with an IC50 value of 14 nM.
KEYWORDS: PKN3 inhibitor compound 16 | Supplier | PKN3 inhibitor | CAS [2361545-75-5] | Non Selective (Phosphorylation substrates) | PKN | Inhibitor | Enzymes | Pancreatic cancer | Prostate cancer | T-cell acute lymphoblastic leukemia

Reference

CRM Asquith et al. Identification of 4-Anilinoquin(az)oline as a Cell-Active Protein Kinase Novel 3 (PKN3) Inhibitor Chemotype. ChemMedChem. 2022 Jun 20;17(12):e202200161.