PKR-IN-C51

• CAT Number: I034860
• CAS Number: 1314594-23-4
• Molecular Formula: C23H21N5
• Molecular Weight: 367.45
• Purity: ≥95%
• Synonyms: N-[2-(1H-indol-3-yl)ethyl]-4-(2-methyl-1H-indol-3-yl)pyrimidin-2-amine
• InChI: InChI=1S/C23H21N5/c1-15-22(18-7-3-5-9-20(18)27-15)21-11-13-25-23(28-21)24-12-10-16-14-26-19-8-4-2-6-17(16)19/h2-9,11,13-14,26-27H,10,12H2,1H3,(H,24,25,28)
• InChIKey: IDAWNFCAFDXMER-UHFFFAOYSA-N
• SMILES: CC1=C(C2=CC=CC=C2N1)C3=NC(=NC=C3)NCCC4=CNC5=CC=CC=C54

PKR-IN-C51（Cat No.:I034860）is a small-molecule inhibitor targeting protein kinase R (PKR), an enzyme involved in the cellular response to stress, including viral infections and inflammation. PKR plays a role in regulating protein synthesis and apoptosis in response to stress signals, making it an essential target for controlling immune and antiviral responses. PKR-IN-C51 inhibits PKR activity, potentially reducing excessive inflammatory responses and viral replication. This compound is under investigation for its therapeutic potential in treating viral infections, autoimmune diseases, and certain cancers by modulating the PKR-mediated signaling pathways.