For research use only. Not for therapeutic Use.
Plecanatide acetate (Cat.No:I019543) is a synthetic peptide analog used for the treatment of chronic idiopathic constipation and irritable bowel syndrome with constipation. It acts as a guanylate cyclase-C agonist, stimulating fluid secretion in the intestines and promoting bowel movement. Plecanatide acetate has demonstrated efficacy in clinical trials and offers a new therapeutic option for gastrointestinal disorders.
| Catalog Number | I019543 |
| CAS Number | 1075732-84-1 |
| Molecular Formula | C₆₇H₁₀₈N₁₈O₂₈S₄ |
| Purity | ≥95% |
| Target | Guanylate Cyclase |
| Reference | [1]. Shailubhai K, et al. Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis. World J Gastrointest Pharmacol Ther. 2015 Nov 6;6(4):213-22.<br>[2]. Rao SSC. Plecanatide: a new guanylate cyclase agonist for the treatment of chronic idiopathic constipation. Therap Adv Gastroenterol. 2018 Jun 8;11:1756284818777945.<br>[3]. Shailubhai K, et, al. Plecanatide, an oral guanylate cyclase C agonist acting locally in the gastrointestinal tract, is safe. Dig Dis Sci. 2013 Sep;58(9):2580-6. |
