PLGA

• CAT Number: I020452
• CAS Number: 34346-01-5
• Purity: ≥95%
• IUPAC Name: 2-hydroxyacetic acid;2-hydroxypropanoic acid
• InChI: InChI=1S/C3H6O3.C2H4O3/c1-2(4)3(5)6;3-1-2(4)5/h2,4H,1H3,(H,5,6);3H,1H2,(H,4,5)
• InChIKey: XBBVURRQGJPTHH-UHFFFAOYSA-N
• SMILES: CC(C(=O)O)O.C(C(=O)O)O

Poly(lactic-co-glycolic acid) (PLGA)(CAT: I020452) is a biodegradable and biocompatible copolymer widely used in pharmaceutical and biomedical applications. Known for its ability to deliver drugs, proteins, and vaccines with controlled release profiles, PLGA is a versatile polymer that degrades into lactic acid and glycolic acid, both of which are naturally metabolized by the body. This property makes PLGA an ideal choice for creating drug delivery systems, such as nanoparticles, microspheres, and implants. Its tunable degradation rate and mechanical properties can be customized by adjusting the ratio of lactic acid to glycolic acid, offering researchers and developers a reliable material for various medical applications, including tissue engineering, regenerative medicine, and sustained drug delivery.

Reference

[1]. Makadia HK, et al. Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier. Polymers (Basel). 2011 Sep 1;3(3):1377-1397.