For research use only. Not for therapeutic Use.
PMSF is an irreversible serine/cysteine protease inhibitor.<br>Although human trypsin is less susceptible to inhibition by PMSF, PMSF rapidly inactivates purified chymotrypsin from human pancreas. PMSF also rapidly inhibits acetylcholinesterase from human red cells.<br>Intraperitoneal injection of PMSF produces dose-dependent analgesia in Sprague-Dawley rats. PMSF significantly enhances the analgesic effect of beta-endorphin (END) in rats.
Catalog Number | A000800 |
CAS Number | 329-98-6 |
Synonyms | Phenylmethylsulfonyl Fluoride |
Molecular Formula | C₇H₇FO₂S |
Purity | ≥95% |
Target | Cathepsin |
Solubility | Soluble in DMSO > 10 mM |
Storage | 3 years -20C powder |
InChI | InChI=1S/C7H7FO2S/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2 |
InChIKey | YBYRMVIVWMBXKQ-UHFFFAOYSA-N |
SMILES | C1=CC=C(C=C1)CS(=O)(=O)F |