For research use only. Not for therapeutic Use.
PNU-101603（Cat No.:I042669）is a small molecule inhibitor targeting the phosphoinositide 3-kinase (PI3K) pathway, which plays a critical role in regulating cell growth, survival, and metabolism. Dysregulation of the PI3K pathway is implicated in various cancers and other diseases. By inhibiting PI3K, PNU-101603 aims to block tumor cell proliferation and survival, offering a potential therapeutic option for cancers, including breast, prostate, and lung cancer. Currently undergoing preclinical and clinical studies, PNU-101603 is being investigated for its ability to improve treatment outcomes in PI3K-driven malignancies and other conditions involving this pathway.
| CAS Number | 168828-60-2 |
| Synonyms | N-[[(5S)-3-[3-fluoro-4-(1-oxo-1,4-thiazinan-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide |
| Molecular Formula | C16H20FN3O4S |
| Purity | ≥95% |
| IUPAC Name | N-[[(5S)-3-[3-fluoro-4-(1-oxo-1,4-thiazinan-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide |
| InChI | InChI=1S/C16H20FN3O4S/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-25(23)7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1 |
| InChIKey | WNRIDZUNMXATND-ZDUSSCGKSA-N |
| SMILES | CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCS(=O)CC3)F |
