Polydatin

• CAT Number: I002933
• CAS Number: 27208-80-6
• Molecular Formula: C20H22O8
• Molecular Weight: 390.388
• Purity: ≥95%
• Synonyms: trans-Resveratrol-3-O-β-D-Glucopyranoside
• Target: Apoptosis
• Solubility: DMSO: ≥ 29 mg/mL
• Storage: -20°C
• IUPAC Name: (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
• InChI: InChI=1S/C20H22O8/c21-10-16-17(24)18(25)19(26)20(28-16)27-15-8-12(7-14(23)9-15)2-1-11-3-5-13(22)6-4-11/h1-9,16-26H,10H2/b2-1+/t16-,17-,18+,19-,20-/m1/s1
• InChIKey: HSTZMXCBWJGKHG-CUYWLFDKSA-N
• SMILES: C1=CC(=CC=C1C=CC2=CC(=CC(=C2)OC3C(C(C(C(O3)CO)O)O)O)O)O

Polydatin（Cat No.:I002933）, also known as Piceid, is a natural compound extracted from the roots of Polygonum cuspidatum Sieb, a plant commonly used in traditional Chinese medicine. It exhibits anti-inflammatory activity in various experimental models. Polydatin has been shown to reduce inflammation by inhibiting the production of pro-inflammatory cytokines and suppressing the activation of inflammatory pathways. Due to its anti-inflammatory properties, polydatin holds potential as a therapeutic agent for the treatment of inflammatory conditions and diseases.

Reference

[1]. Cheng Y, et al. Involvement of cell adhesion molecules in polydatin protection of brain tissues from ischemia-reperfusion
injury. Brain Res. 2006 Sep 19;1110(1):193-200.

[2]. Wang HL, et al. Synergistic effects of Polydatin and Vitamin C in Inhibiting Cardiotoxicity induced by Doxorubicin in rats. Fundam Clin Pharmacol. 2016 Nov 28. [Epub ahead of print]

[3]. Jiang KF, et al. Polydatin ameliorates Staphylococcus aureus-induced mastitis in mice via inhibiting TLR2-mediated activation of the p38 MAPK/NF-κB pathway. Acta Pharmacol Sin. 2016 Nov 28. [Epub ahead of print]