For research use only. Not for therapeutic Use.
Polymyxin B2 sulfate is one of several polypeptide components that comprises the antibiotic polymyxin B sulfate. The unique fatty acid moiety found in polymyxin B2 is 6-methylheptanoic acid (6-MHA). Results from <em>i</em><em>n vitro</em> studies have shown marginal differences in MIC data when comparing the fractions.</br>Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram negative bacteria leading to lysing of the cell. Polymyxin B only needs to interact with LPS, it is not required to enter the cell.
| Catalog Number | R000909 |
| Molecular Formula | C55H96N16O13 xH2SO4 (lot specific) |
| Purity | ≥95% |
| Storage | -20°C |
| Reference | <p>Newton, B. A. /The Properties and Mode of Action of the Polymyxins./<em> Bacteriology Reviews</em> (n.d.): 14-27. <em>www.ncbi.gov</em>. Web. 21 Aug. 2012.</p><p>Selim S., Negrel J., Govaerts C., Gianinazzi S. and Tuinen van D., 2005, Isolation and Partial Characterization of Antagonistic Peptides Produced by Paenibacillus sp. Strain B2 Isolated from the Sorghum Mycorrhizosphere. <em>Applied and Environmental Microbiology</em>, Nov. 2005, p. 6501–6507</p><p> |
