For research use only. Not for therapeutic Use.
Polyphyllin H has been widely used in traditional Chinese medicinal preparations to treat inflammation, fracture and convulsion[1].
| Catalog Number | I014881 |
| CAS Number | 81917-50-2 |
| Synonyms | (2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-5-[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)-2-[(1R,2S,4S,5’R,6R,7S,8S,9S,12S,13R,16S)-8-hydroxy-5′,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2′-oxane]-16-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol |
| Molecular Formula | C44H70O17 |
| Purity | ≥95% |
| InChI | InChI=1S/C44H70O17/c1-19-8-13-43(54-18-19)21(3)44(53)29(61-43)15-26-24-7-6-22-14-23(9-11-41(22,4)25(24)10-12-42(26,44)5)56-40-37(60-38-34(51)32(49)30(47)20(2)55-38)35(52)36(28(17-46)58-40)59-39-33(50)31(48)27(16-45)57-39/h6,19-21,23-40,45-53H,7-18H2,1-5H3/t19-,20+,21-,23+,24-,25+,26+,27+,28-,29+,30+,31+,32-,33-,34-,35+,36-,37-,38+,39+,40-,41+,42+,43-,44-/m1/s1 |
| InChIKey | DEUSODBYLVUUQI-CRUCUECZSA-N |
| SMILES | CC1CCC2(C(C3(C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(O8)CO)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)O)C)OC1 |
| Reference | [1]. Xingbin Yin, et al. Analysis and Pharmacokinetic Study of Polyphyllin H in Beagle Dog Plasma After Oral Administration of Rhizoma Paridis Extracts by LC-MS/MS. Biomed Chromatogr. 2014 Dec;28(12):1869-73. |
