Polyphyllin II

• CAT Number: R014413
• CAS Number: 76296-72-5
• Molecular Formula: C44H70O16
• Molecular Weight: 855.028
• Purity: ≥95%
• Synonyms: Polyphyllin D; (3β,25R)-Spirost-5-en-3-yl O-α-L-arabinofuranosyl-(1→4)-O-[6-deoxy-α-L-mannopyranosyl-(1→3)]-β-D-glucopyranoside
• Target: Apoptosis
• Storage: -20°C
• InChI: InChI=1S/C44H70O16/c1-19-8-13-44(53-18-19)20(2)30-27(60-44)15-26-24-7-6-22-14-23(9-11-42(22,4)25(24)10-12-43(26,30)5)55-41-36(52)38(59-39-35(51)33(49)31(47)21(3)54-39)37(29(17-46)57-41)58-40-34(50)32(48)28(16-45)56-40/h6,19-21,23-41,45-52H,7-18H2,1-5H3
• InChIKey: AWKXNOOUWFJCMU-UHFFFAOYSA-N
• SMILES: CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(O8)CO)O)O)OC9C(C(C(C(O9)C)O)O)O)O)C)C)C)OC1

Polyphyllin II (CAT: R014413) is a bioactive steroidal saponin found in plants like Paris species. With potential in traditional medicine and research, it displays cytotoxicity, inducing apoptosis and disrupting cell cycles in cancer cells. Its immunomodulatory and anti-inflammatory effects hint at broader applications. While mechanisms are studied, Polyphyllin II holds promise for drug discovery, particularly in oncology and immune-related disorders. Comprehensive research is vital to unveil its full pharmacologic potential and ensure safe utilization.