Polyporenic acid C

• CAT Number: I017075
• CAS Number: 465-18-9
• Molecular Formula: C₃₁H₄₆O₄
• Molecular Weight: 482.69
• Purity: ≥95%
• Target: Apoptosis
• Storage: 4°C, protect from light
• IUPAC Name: (2R)-2-[(5R,10S,13R,14R,16R,17R)-16-hydroxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid
• InChI: InChI=1S/C31H46O4/c1-18(2)19(3)9-10-20(27(34)35)26-23(32)17-31(8)22-11-12-24-28(4,5)25(33)14-15-29(24,6)21(22)13-16-30(26,31)7/h11,13,18,20,23-24,26,32H,3,9-10,12,14-17H2,1-2,4-8H3,(H,34,35)/t20-,23-,24+,26+,29-,30-,31+/m1/s1
• InChIKey: KPKYWYZPIVAHKU-WMNQUVFJSA-N
• SMILES: CC(C)C(=C)CCC(C1C(CC2(C1(CC=C3C2=CCC4C3(CCC(=O)C4(C)C)C)C)C)O)C(=O)O

Polyporenic acid C（Cat No.:I017075） is a triterpene derived from P.cocos that induces apoptosis via the death receptor-mediated apoptosis pathway, without the involvement of mitochondria. It has shown potential for use in lung cancer research due to its ability to induce apoptosis in cancer cells. It is thought that Polyporenic acid C may have therapeutic potential as a natural product-derived anticancer agent, though further research is needed to fully understand its mechanisms of action and potential clinical applications.

Reference

[1]. Ling H, et al. Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells.Mol Carcinog. 2009 Jun;48(6):498-507.