Pomalidomide-amido-C5-PEG2-C6-chlorine

• CAT Number: I040629
• CAS Number: 1835705-69-5
• Molecular Formula: C29H40ClN3O8
• Molecular Weight: 594.10
• Purity: ≥95%
• Synonyms: 6-[2-[2-(6-chlorohexoxy)ethoxy]ethoxy]-N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]hexanamide
• InChI: InChI=1S/C29H40ClN3O8/c30-14-5-1-2-6-15-39-17-19-41-20-18-40-16-7-3-4-11-24(34)31-22-10-8-9-21-26(22)29(38)33(28(21)37)23-12-13-25(35)32-27(23)36/h8-10,23H,1-7,11-20H2,(H,31,34)(H,32,35,36)
• InChIKey: CEGOWZXGBJKMOC-UHFFFAOYSA-N
• SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)CCCCCOCCOCCOCCCCCCCl

Pomalidomide-amido-C5-PEG2-C6-chlorine is a derivant of Pomalidomide (HY-10984)[1].

Reference

[1]. Lai AC, et al. Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL. Angew Chem Int Ed Engl. 2016 Jan 11;55(2):807-10.
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