For research use only. Not for therapeutic Use.
Pomalidomide-C5-azide is an E3 ubiquitin ligase cereblon (CRBN) ligand-Linker conjugate. The azide group can undergo a click chemical reaction[1].
| Catalog Number | I038461 |
| CAS Number | 2434629-02-2 |
| Synonyms | 4-(5-azidopentylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione |
| Molecular Formula | C18H20N6O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H20N6O4/c19-23-21-10-3-1-2-9-20-12-6-4-5-11-15(12)18(28)24(17(11)27)13-7-8-14(25)22-16(13)26/h4-6,13,20H,1-3,7-10H2,(H,22,25,26) |
| InChIKey | XINWYKDRHLFQFY-UHFFFAOYSA-N |
| SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCCCCN=[N+]=[N-] |
| Reference | [1]. Yonghui Sun, et al. Developing potent BTKC481S PROTACs for ibrutinib-resistant malignant lymphoma. Chinese Chemical Letters. Volume 34, Issue 6, June 2023, 107924. |
