For research use only. Not for therapeutic Use.
Pomalidomide-C7-NH2 hydrochloride(CAT: I040954) is a structural derivative of Pomalidomide, an immunomodulatory drug (IMiD) that functions by targeting cereblon (CRBN), leading to the degradation of key transcription factors such as IKZF1 and IKZF3. This mechanism results in anti-proliferative and pro-apoptotic effects, particularly in hematological malignancies. Pomalidomide is widely used for treating multiple myeloma and other cancers due to its immunomodulatory and anti-angiogenic properties. Given its mode of action, Pomalidomide-C7-NH2 hydrochloride is most relevant to Cancer Disease Research, specifically in drug development and medicinal chemistry efforts to enhance the therapeutic profile of IMiDs for oncology applications.
| Catalog Number | I040954 |
| CAS Number | 2446474-05-9 |
| Synonyms | 4-(7-aminoheptylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride |
| Molecular Formula | C20H27ClN4O4 |
| Purity | ≥95% |
| IUPAC Name | 4-(7-aminoheptylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride |
| InChI | InChI=1S/C20H26N4O4.ClH/c21-11-4-2-1-3-5-12-22-14-8-6-7-13-17(14)20(28)24(19(13)27)15-9-10-16(25)23-18(15)26;/h6-8,15,22H,1-5,9-12,21H2,(H,23,25,26);1H |
| InChIKey | QICRZTGJMYJVAT-UHFFFAOYSA-N |
| SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCCCCCCN.Cl |
