For research use only. Not for therapeutic Use.
Pomalidomide-PEG4-COOH is a E3 ligase ligand-linker conjugate. Pomalidomide-PEG4-COOH contains the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology (extracted from patent WO2017184995A1)[1].
| Catalog Number | I025279 |
| CAS Number | 2138440-81-8 |
| Synonyms | 3-[2-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| Molecular Formula | C24H31N3O10 |
| Purity | ≥95% |
| InChI | InChI=1S/C24H31N3O10/c28-19-5-4-18(22(31)26-19)27-23(32)16-2-1-3-17(21(16)24(27)33)25-7-9-35-11-13-37-15-14-36-12-10-34-8-6-20(29)30/h1-3,18,25H,4-15H2,(H,29,30)(H,26,28,31) |
| InChIKey | CAANPUBZFFRWQP-UHFFFAOYSA-N |
| SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCOCCOCCC(=O)O |
| Reference | [1]. Guangrong Zheng, et al.Compounds that induce degradation of anti-apoptotic bcl-2 family proteins and the uses thereof. Patent WO2017184995A1. |
