PP58

• CAT Number: I002636
• CAS Number: 212391-58-7
• Molecular Formula: C22H19Cl2N5O2
• Molecular Weight: 456.32
• Purity: ≥95%
• Target: Src
• Solubility: DMSO
• Storage: Store at -20°C
• IUPAC Name: 2-[4-(2-aminoethoxy)anilino]-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7-one
• InChI: InChI=1S/C22H19Cl2N5O2/c1-29-20-13(11-16(21(29)30)19-17(23)3-2-4-18(19)24)12-26-22(28-20)27-14-5-7-15(8-6-14)31-10-9-25/h2-8,11-12H,9-10,25H2,1H3,(H,26,27,28)
• InChIKey: MAXZESONWXTISA-UHFFFAOYSA-N
• SMILES: CN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=CC=C3Cl)Cl)NC4=CC=C(C=C4)OCCN

PP58（Cat No.:I002636）is a small molecule that acts as a selective inhibitor of the protein phosphatase 2A (PP2A) enzyme. PP2A is a key serine/threonine phosphatase involved in regulating numerous cellular processes, including cell growth, survival, and the response to stress. By inhibiting PP2A, PP58 modulates signaling pathways associated with cancer cell survival, differentiation, and proliferation. It has shown potential as an anticancer agent, particularly in cancers where PP2A is dysregulated. PP58 is currently under investigation in preclinical studies to assess its therapeutic potential and safety in treating various malignancies.