For research use only. Not for therapeutic Use.
PPACK Dihydrochloride(CAT: I011420) is a potent, irreversible inhibitor of serine proteases, particularly thrombin. By covalently modifying the active site of thrombin, it prevents the enzyme from participating in coagulation processes. This makes PPACK Dihydrochloride a valuable tool in hematology and enzymology research, where it is used to study thrombin’s role in blood coagulation, fibrinolysis, and related signaling pathways. Its high specificity and efficacy make it a critical reagent for exploring protease function, developing anticoagulants, and investigating therapeutic strategies for thrombotic and cardiovascular disorders. Proper handling and storage are essential due to its reactive nature.
| Catalog Number | I011420 |
| CAS Number | 142036-63-3 |
| Molecular Formula | C21H31ClN6O3.2HCl |
| Purity | ≥95% |
| Target | Thrombin |
| Solubility | Soluble in HCL |
| Storage | Store at -20°C |
| IUPAC Name | 1-(2-amino-3-phenylpropanoyl)-N-[1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]pyrrolidine-2-carboxamide;dihydrochloride |
| InChI | InChI=1S/C21H31ClN6O3.2ClH/c22-13-18(29)16(8-4-10-26-21(24)25)27-19(30)17-9-5-11-28(17)20(31)15(23)12-14-6-2-1-3-7-14;;/h1-3,6-7,15-17H,4-5,8-13,23H2,(H,27,30)(H4,24,25,26);2*1H |
| InChIKey | XKDCRQWZLPWLFG-UHFFFAOYSA-N |
| SMILES | C1CC(N(C1)C(CCCN=C(N)N)C(=O)CCl)C(=O)NC(=O)C(CC2=CC=CC=C2)N |
