For research use only. Not for therapeutic Use.
PPC-NB is a glutathione cleavable linker used for the antibody-drug conjugate (ADC)[1].
| Catalog Number | I046043 |
| CAS Number | 1887040-81-4 |
| Synonyms | (4-nitrophenyl) 2-(pyridin-2-yldisulfanyl)propyl carbonate |
| Molecular Formula | C15H14N2O5S2 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H14N2O5S2/c1-11(23-24-14-4-2-3-9-16-14)10-21-15(18)22-13-7-5-12(6-8-13)17(19)20/h2-9,11H,10H2,1H3 |
| InChIKey | AFINOVIFQZMCHN-UHFFFAOYSA-N |
| SMILES | CC(COC(=O)OC1=CC=C(C=C1)[N+](=O)[O-])SSC2=CC=CC=N2 |
| Reference | [1]. Robert A. Volkmann, et al. Compounds, compositions, and methods for treatment of diseases involving acidic or hypoxic diseased tissues. WO2019136298A1. |
