For research use only. Not for therapeutic Use.
Selective inactivator of human cytochrome P450 2B6 (CYP2B6)
| Catalog Number | I047547 |
| CAS Number | 21602-56-2 |
| Molecular Formula | C14H21N.HCl |
| Purity | ≥95% |
| IUPAC Name | 1-(2-phenylpropan-2-yl)piperidine;hydrochloride |
| InChI | InChI=1S/C14H21N.ClH/c1-14(2,13-9-5-3-6-10-13)15-11-7-4-8-12-15;/h3,5-6,9-10H,4,7-8,11-12H2,1-2H3;1H |
| SMILES | CC(C)(C1=CC=CC=C1)N2CCCCC2.Cl |
| Reference | RL Walsky and RS Obach. A Comparison of PPP, 1,1′,1″-Phosphinothioylidynetrisaziridine (ThioTEPA), Clopidogrel, and Ticlopidine as Selective Inactivators of Human Cytochrome P450 2B6. Drug Metab. Dsipos. (DMD). 2007, 35(11), 2053-2059.
J Chun et al. Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by 2-phenyl-2-(1-piperidinyl)propane. Drug Metab Dispos. 2000, 28(8), 905-911. |
