PPTN hydrochloride

• CAT Number: I011043
• Molecular Formula: C29H24F3NO2.HCl
• Molecular Weight: 511.96
• Purity: ≥95%
• Synonyms: 4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid hydrochloride
• Solubility: Soluble to 100 mM in DMSO and to 20 mM in ethanol
• Storage: Store at -20°C
• IUPAC Name: 4-(4-piperidin-4-ylphenyl)-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid;hydrochloride
• InChI: InChI=1S/C29H24F3NO2.ClH/c30-29(31,32)25-8-5-19(6-9-25)22-7-10-26-23(15-22)16-24(28(34)35)17-27(26)21-3-1-18(2-4-21)20-11-13-33-14-12-20;/h1-10,15-17,20,33H,11-14H2,(H,34,35);1H
• InChIKey: FKMVYPCBLWYNAV-UHFFFAOYSA-N
• SMILES: C1CNCCC1C2=CC=C(C=C2)C3=C4C=CC(=CC4=CC(=C3)C(=O)O)C5=CC=C(C=C5)C(F)(F)F.Cl

PPTN hydrochloride(CAT: I011043) is a high-affinity and selective P2Y14 receptor antagonist. The P2Y14 receptor is a G protein-coupled receptor (GPCR) primarily activated by UDP-sugars and is involved in regulating immune responses, inflammation, and glucose metabolism. By selectively blocking P2Y14, PPTN hydrochloride inhibits receptor-mediated signaling pathways, making it a valuable tool in immunology and inflammatory disease research. It is particularly useful for studying the role of P2Y14 in conditions like asthma, chronic inflammation, and metabolic disorders, offering potential therapeutic strategies to modulate immune function and inflammatory responses.