For research use only. Not for therapeutic Use.
High affinity and selective P2Y<sub>14</sub> antagonist (K<sub>B</sub> = 434 pM). Exhibits >10,000-fold selectivity for P2Y<sub>14</sub> over other P2Y receptors. Inhibits UDP-glucose and MRS 2690-induced porcine pancreatic artery contraction <em>ex vivo</em>. Also blocks UDP-glucose-induced chemotaxis of HL-60 leukemia cells <em>in vitro</em>.
| Catalog Number | I011043 |
| Synonyms | 4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid hydrochloride |
| Molecular Formula | C29H24F3NO2.HCl |
| Purity | ≥95% |
| Solubility | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| Storage | Store at -20°C |
