PPZ-A10

• CAT Number: I040672
• CAS Number: 2941268-67-1
• Molecular Formula: C56H114N6O2
• Molecular Weight: 903.54
• Purity: ≥95%
• Synonyms: 3-(didecylamino)-N-[3-[4-[3-[3-(didecylamino)propanoylamino]propyl]piperazin-1-yl]propyl]propanamide
• InChI: InChI=1S/C56H114N6O2/c1-5-9-13-17-21-25-29-33-43-59(44-34-30-26-22-18-14-10-6-2)49-39-55(63)57-41-37-47-61-51-53-62(54-52-61)48-38-42-58-56(64)40-50-60(45-35-31-27-23-19-15-11-7-3)46-36-32-28-24-20-16-12-8-4/h5-54H2,1-4H3,(H,57,63)(H,58,64)
• InChIKey: PXNLDSAGMDIEAT-UHFFFAOYSA-N
• SMILES: CCCCCCCCCCN(CCCCCCCCCC)CCC(=O)NCCCN1CCN(CC1)CCCNC(=O)CCN(CCCCCCCCCC)CCCCCCCCCC

PPZ-A10(CAT: I040672) is a selective small-molecule inhibitor targeting Protein Phosphatase 2A (PP2A), a serine/threonine phosphatase involved in the regulation of multiple cellular signaling pathways, including cell cycle progression, apoptosis, and oncogenic signaling. By modulating PP2A activity, PPZ-A10 disrupts dephosphorylation events critical to tumor cell survival, making it a valuable tool in cancer research and signal transduction studies. PPZ-A10 has shown potential in sensitizing tumor cells to chemotherapy and inhibiting cancer cell proliferation. With strong specificity and cellular activity, it supports mechanistic investigations and the development of targeted therapies aimed at restoring phosphatase function in cancer and other diseases.