For research use only. Not for therapeutic Use.
PPZ2(CAT: I034971) is a novel and selective activator of DAG-activated TRPC3, TRPC6, and TRPC7 channels, extensively utilized in ion channel and neurophysiology research. By directly targeting these transient receptor potential canonical (TRPC) channels, it facilitates the study of calcium signaling pathways involved in cellular excitability, neurotransmission, and various physiological processes. PPZ2 is particularly valuable for exploring TRPC-mediated mechanisms in cardiovascular function, neuronal activity, and pathological conditions such as fibrosis and neurological disorders. Its specificity and efficacy make it a critical tool for preclinical studies aimed at advancing the understanding of TRPC channel regulation and therapeutic potential.
| CAS Number | 896203-18-2 |
| Synonyms | PPZ 2; PPZ-2; PPZ2 |
| Molecular Formula | C22H29N3O2 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 2-[4-(2,3-Dimethylphenyl)piperazin-1-yl]-N-(2-ethoxyphenyl)acetamide |
| InChI | InChI=1S/C22H29N3O2/c1-4-27-21-11-6-5-9-19(21)23-22(26)16-24-12-14-25(15-13-24)20-10-7-8-17(2)18(20)3/h5-11H,4,12-16H2,1-3H3,(H,23,26) |
| InChIKey | FVNDSDZIAJJKNY-UHFFFAOYSA-N |
| SMILES | O=C(NC1=CC=CC=C1OCC)CN2CCN(C3=CC=CC(C)=C3C)CC2 |
