For research use only. Not for therapeutic Use.
PqsR/LasR-IN-2 (Compound 3) is a potent inhibitor of PqsR and LasR systems in P. aeruginosa. PqsR/LasR-IN-2 also inhibits hERG with the IC50 of 1.408 µM[1].
| Catalog Number | I043695 |
| CAS Number | 2071705-93-4 |
| Synonyms | (E)-1-[2-[2-(4-butan-2-ylphenoxy)ethoxy]-5-chlorophenyl]-N-(1,2,4-triazol-4-yl)methanimine |
| Molecular Formula | C21H23ClN4O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H23ClN4O2/c1-3-16(2)17-4-7-20(8-5-17)27-10-11-28-21-9-6-19(22)12-18(21)13-25-26-14-23-24-15-26/h4-9,12-16H,3,10-11H2,1-2H3/b25-13+ |
| InChIKey | DLQFXDYTUCWLFI-DHRITJCHSA-N |
| SMILES | CCC(C)C1=CC=C(C=C1)OCCOC2=C(C=C(C=C2)Cl)C=NN3C=NN=C3 |
| Reference | [1]. Mohammad Anwar Hossain, et al. Design, synthesis, and evaluation of compounds capable of reducing Pseudomonas aeruginosa virulence. Eur J Med Chem. 2020 Jan 1;185:111800. |
