For research use only. Not for therapeutic Use.
Pralidoxime chloride(Cat No.:A000063), is a pharmaceutical compound used as an antidote for organophosphate and carbamate pesticide poisoning. It works by reactivating acetylcholinesterase, an enzyme that helps regulate nerve signals, which is inhibited by these toxins. Pralidoxime chloride can reverse the toxic effects of these chemicals, such as muscle weakness and respiratory distress, by restoring proper nerve function. It is often administered in combination with other treatments, like atropine, to manage pesticide poisoning.
Catalog Number | A000063 |
CAS Number | 51-15-0 |
Synonyms | 2-PAM (chloride) |
Molecular Formula | C7H9ClN2O |
Purity | ≥95% |
Target | Cholinesterase (ChE) |
Storage | Room Temperature |
IUPAC Name | (NE)-N-[(1-methylpyridin-1-ium-2-yl)methylidene]hydroxylamine;chloride |
InChI | InChI=1S/C7H8N2O.ClH/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H,1H3;1H |
InChIKey | HIGSLXSBYYMVKI-UHFFFAOYSA-N |
SMILES | C[N+]1=CC=CC=C1C=NO.[Cl-] |
Reference | 1: Zheng Q, Chen Y, Fan K, Wu J, Ying Y. Exploring pralidoxime chloride as a 2: Uwaydah NI, Hoskins SL, Bruttig SP, Farrar H, Copper NC, Deyo DJ, Dubick MA, 3: Liu HX, Liu CF, Yang WH. Clinical study of continuous micropump infusion of 4: Banerjee S, Chattopadhyay P, Ghosh A, Bhatnagar A, Veer V. Pharmacokinetic and 5: Banerjee S, Chattopadhyay P, Ghosh A, Pathak MP, Gogoi J, Veer V. Protection 6: Lucyk S, Vilensky D, Fok PT, Nelson LS. Reactivation of plasma 7: Connors NJ, Weber BJ, Hoffman RS. Regarding /Repeated pulse intramuscular 8: Konickx LA, Worek F, Jayamanne S, Thiermann H, Buckley NA, Eddleston M. <br> 10: Banerjee S, Chattopadhyay P, Ghosh A, Kaity S, Veer V. Development and |