For research use only. Not for therapeutic Use.
Prasterone sulfate (Cat.No:I008841), also known as dehydroepiandrosterone sulfate (DHEA-S), is a naturally occurring steroid hormone produced by the adrenal glands. It serves as a precursor for the synthesis of other hormones in the body. Prasterone sulfate supplements are sometimes used to address age-related conditions and hormonal imbalances.
| Catalog Number | I008841 |
| CAS Number | 651-48-9 |
| Synonyms | PB-005; PB005; PB 005; DHEAS;(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl hydrogen sulfate |
| Molecular Formula | C19H28O5S |
| Purity | ≥95% |
| Target | Endogenous Metabolite |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4 °C for short term, or -20 °C for long term |
| IUPAC Name | [(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] hydrogen sulfate |
| InChI | InChI=1S/C19H28O5S/c1-18-9-7-13(24-25(21,22)23)11-12(18)3-4-14-15-5-6-17(20)19(15,2)10-8-16(14)18/h3,13-16H,4-11H2,1-2H3,(H,21,22,23)/t13-,14-,15-,16-,18-,19-/m0/s1 |
| InChIKey | CZWCKYRVOZZJNM-USOAJAOKSA-N |
| SMILES | CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)OS(=O)(=O)O)C |
| Reference | </br>1:[The effect of sodium prasterone sulfate on lactation]. Gu H, Li Y, Rong L.Zhonghua Fu Chan Ke Za Zhi. 1995 Apr;30(4):197-9. Chinese. PMID: 7664601 </br>2:Contributions of various serum proteins to the binding of prasterone sulfate in humans. Sakai T, Adachi Y, Yatomi M, Awata N.Chem Pharm Bull (Tokyo). 1992 Oct;40(10):2864-5. PMID: 1464119 </br>3:The biological fate of sodium prasterone sulfate after vaginal administration. I. Absorption and excretion in rats. Sakaguchi M, Sakai T, Adachi Y, Kawashima T, Awata N.J Pharmacobiodyn. 1992 Feb;15(2):67-73. PMID: 1403604 </br>4:The effects of grinding and drying on the solid state stability of sodium prasterone sulfate. Nakagawa H, Takahashi Y, Sugimoto I.Chem Pharm Bull (Tokyo). 1982 Jan;30(1):242-8. No abstract available. PMID: 6211259 </br>5:Stability of lyophilized sodium prasterone sulfate. Sugimoto I, Ishihara T, Habata H, Nakagawa H.J Parenter Sci Technol. 1981 May-Jun;35(3):88-92. No abstract available. PMID: 6453961 |
