Pravastatin

For research use only. Not for therapeutic Use.

  • CAT Number: I004947
  • CAS Number: 81093-37-0
  • Molecular Formula: C23H36O7
  • Molecular Weight: 424.50
  • Purity: ≥95%
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Pravastatin(Cat No.:I004947)is a cholesterol-lowering medication belonging to the statin class, widely used to manage hyperlipidemia and reduce cardiovascular risk. By inhibiting HMG-CoA reductase, an enzyme essential in cholesterol biosynthesis, pravastatin effectively lowers LDL cholesterol and total cholesterol levels, promoting better heart health. Unlike other statins, pravastatin is hydrophilic, which may reduce its muscle-related side effects and interactions with the central nervous system. Its favorable safety profile makes it suitable for patients with additional risk factors for cardiovascular disease, offering protection against heart attack and stroke when used long-term.


Catalog Number I004947
CAS Number 81093-37-0
Synonyms

(3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid

Molecular Formula C23H36O7
Purity ≥95%
Target Metabolic Enzyme/Protease
Solubility 10 mM in DMSO
Storage Store at -20C
IUPAC Name (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid
InChI InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1
InChIKey TUZYXOIXSAXUGO-PZAWKZKUSA-N
SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)O)O)O)O
Reference

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<br>[1]. McTavish D, et al. Pravastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia. Drugs. 1991 Jul;42(1):65-89.

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