For research use only. Not for therapeutic Use.
Pravastatin（Cat No.:I004947）is a cholesterol-lowering medication belonging to the statin class, widely used to manage hyperlipidemia and reduce cardiovascular risk. By inhibiting HMG-CoA reductase, an enzyme essential in cholesterol biosynthesis, pravastatin effectively lowers LDL cholesterol and total cholesterol levels, promoting better heart health. Unlike other statins, pravastatin is hydrophilic, which may reduce its muscle-related side effects and interactions with the central nervous system. Its favorable safety profile makes it suitable for patients with additional risk factors for cardiovascular disease, offering protection against heart attack and stroke when used long-term.
| Catalog Number | I004947 |
| CAS Number | 81093-37-0 |
| Synonyms | (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid |
| Molecular Formula | C23H36O7 |
| Purity | ≥95% |
| Target | HMG-CoA Reductase |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20C |
| IUPAC Name | (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid |
| InChI | InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1 |
| InChIKey | TUZYXOIXSAXUGO-PZAWKZKUSA-N |
| SMILES | CC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)O)O)O)O |
| Reference | <p style=/line-height:25px/> </p> |
