For research use only. Not for therapeutic Use.
Prazosin Hydrochloride(Cat No.:A000734)is an alpha-1 adrenergic receptor antagonist primarily used to treat hypertension and related cardiovascular conditions. By blocking alpha-1 receptors, it relaxes blood vessels, leading to a decrease in blood pressure and improved blood flow. Prazosin is also used to manage symptoms of benign prostatic hyperplasia (BPH) by relaxing smooth muscle in the bladder neck and prostate. Additionally, it is effective in treating post-traumatic stress disorder (PTSD)-related nightmares and anxiety. Its versatile therapeutic effects make it a valuable medication in both cardiovascular and psychiatric care.
Catalog Number | A000734 |
CAS Number | 19237-84-4 |
Synonyms | 19237-84-4; Prazosin HCl; Vasoflex; Minipress; Peripress |
Molecular Formula | C19H22ClN5O4 |
Purity | ≥95% |
Target | Neuronal Signaling |
Solubility | Limited solubility |
Storage | -20°C |
IUPAC Name | [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone;hydrochloride |
InChI | InChI=1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H |
InChIKey | WFXFYZULCQKPIP-UHFFFAOYSA-N |
SMILES | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N)OC.Cl |
Reference | 1: Shen X, Xu Q, Xu S, Li J, Zhang N, Zhang L. Preparation and transdermal <br> 3: Kabbaj M, Morley-Fletcher S, Le Moal M, Maccari S. Individual differences in 4: Liu L, Wang J, Zhu S. Delivery of prazosin hydrochloride from osmotic pump 5: Liu L, Zhu S. Preparation and characterization of inclusion complexes of <br> 7: Legnerová Z, Huclová J, Thun R, Solich P. Sensitive fluorimetric method based 8: Reddy LH, Ghosh B. Enhancer aided in vitro permeation of atenolol and prazosin 9: Kataoka H, Kumagai H, Hanai H. Treating familial Mediterranean fever with 10: Altiokka G, Tunçel M. Differential pulse polarographic determination of |