Prazosin

• CAT Number: I002459
• CAS Number: 19216-56-9
• Molecular Formula: C19H21N5O4
• Molecular Weight: 383.4
• Purity: ≥95%
• Synonyms: [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone
• Target: Adrenergic Receptor
• Solubility: 10 mM in DMSO
• Storage: Store at -20C

Prazosin (Cat.No:I002459) is an alpha-1 adrenergic receptor blocker used primarily in the treatment of hypertension and benign prostatic hyperplasia (BPH). It works by relaxing and widening blood vessels, reducing blood pressure. Prazosin is also sometimes prescribed off-label for the management of nightmares and post-traumatic stress disorder (PTSD) symptoms.

Reference

[1]. Day HE, et al. Distribution of alpha 1a-, alpha 1b- and alpha 1d-adrenergic receptor mRNA in the rat brain and spinal cord. J Chem Neuroanat. 1997 Jul;13(2):115-39.
[2]. Yu CX, et al. Selective MT(2) melatonin receptor antagonist blocks melatonin-induced antinociception in rats. Neurosci Lett. 2000 Mar 24;282(3):161-4.