For research use only. Not for therapeutic Use.
Preclamol hydrochloride ((-)-3-PPP hydrochloride) is a selective dopamine autoreceptor agonist. Preclamol hydrochloride has the potential for the research of schizophrenia[1][2].
| Catalog Number | I041328 |
| CAS Number | 88768-67-6 |
| Synonyms | 3-[(3S)-1-propylpiperidin-3-yl]phenol;hydrochloride |
| Molecular Formula | C14H22ClNO |
| Purity | ≥95% |
| InChI | InChI=1S/C14H21NO.ClH/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12;/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3;1H/t13-;/m1./s1 |
| InChIKey | NRHUDETYKUBQJT-BTQNPOSSSA-N |
| SMILES | CCCN1CCCC(C1)C2=CC(=CC=C2)O.Cl |
| Reference | [1]. Seth-Olov Thorberg, et al. Large scale synthesis and absolute configuration of (-)-3-ppp, a selective dopamine autoreceptor agonist. Tetrahedron. 1985, 41(1): 129-139. [2]. Tamminga CA, et al. Pharmacologic properties of (-)-3PPP (preclamol) in man. J Neural Transm Gen Sect. 1992;88(3):165-75. |
