Prednisone-d8

• CAT Number: S000836
• Molecular Formula: C21H18D8O5
• Molecular Weight: 366.48
• Purity: ≥95%
• IUPAC Name: (6S,8S,9S,10R,13S,14S,17R)-2,4,6,9,12,12-hexadeuterio-17-(2,2-dideuterio-2-hydroxyacetyl)-17-hydroxy-10,13-dimethyl-6,7,8,14,15,16-hexahydrocyclopenta[a]phenanthrene-3,11-dione
• InChI: InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1/i3D,5D,9D,10D2,11D2,18D/t3-,14-,15-,18+,19-,20-,21-
• InChIKey: XOFYZVNMUHMLCC-VBMKQEIHSA-N
• SMILES: CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C

Prednisone-d8（Cat No.:S000836） is a deuterated form of prednisone, where eight hydrogen atoms are replaced with deuterium, resulting in the molecular formula C21H18D8O5. This stable isotope-labeled glucocorticoid is primarily used in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy to enhance detection and quantification in pharmacokinetic and metabolic studies. Prednisone-d8 serves as a valuable tool in pharmaceutical research, providing critical insights into the drug’s metabolism, distribution, and elimination. It is particularly useful in the development and optimization of therapeutic regimens for conditions like autoimmune diseases and inflammatory disorders.