For research use only. Not for therapeutic Use.
Prexigebersen sodium is an antisense oligonucleotide designed to inhibit protein synthesis of Grb2 (growth factor receptor bound protein 2).
| Catalog Number | I040300 |
| Molecular Formula | C177H206N63Na18O110P17 |
| Purity | ≥95% |
| Reference | [1]. Maro Ohanian, Tara L. Lin, Ellen Ritchie, et al. Pierce, Ana Tari Ashizawa, Hagop Kantarjian, Jorge E. Cortes, Gail J. Roboz; Safety and Efficacy of Lower Intensity Induction Therapy with Intravenous Prexigebersen (BP1001) in Patients with High-Risk and Relapsed/Refractory Acute Myeloid Leukemia (AML). Blood 2021; 138 (Supplement 1): 1281. [2]. Tremblay G, Khalafaghian G, Legault J, Nielsen P, Bartlett A. Dual ligation hybridization assay for the specific determination of oligonucleotide therapeutics. Bioanalysis. 2011;3(5):499-508. |
