For research use only. Not for therapeutic Use.
Primidolol(CAT: I008875) is a beta-adrenergic receptor antagonist (beta-blocker) with additional intrinsic sympathomimetic activity. It is used in cardiovascular research to study its effects on conditions like hypertension and arrhythmias. By modulating beta-adrenergic receptors, Primidolol reduces heart rate and myocardial oxygen demand, providing a therapeutic approach for managing cardiac stress. Its dual action as a beta-blocker and partial agonist makes it a valuable compound for investigating adrenergic signaling pathways and the development of treatments for cardiovascular disorders.
| CAS Number | 67227-55-8 |
| Synonyms | Primidolol; Primidololum; UK-11,443.;1-(2-((2-Hydroxy-3-(o-tolyloxy)propyl)amino)ethyl)thymine |
| Molecular Formula | C17H23N3O4 |
| Purity | ≥95% |
| Target | Beta Adrenergic Receptor Antagonist |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4 °C for short term, or -20 °C for long term |
| IUPAC Name | 1-[2-[[2-hydroxy-3-(2-methylphenoxy)propyl]amino]ethyl]-5-methylpyrimidine-2,4-dione |
| InChI | InChI=1S/C17H23N3O4/c1-12-5-3-4-6-15(12)24-11-14(21)9-18-7-8-20-10-13(2)16(22)19-17(20)23/h3-6,10,14,18,21H,7-9,11H2,1-2H3,(H,19,22,23) |
| InChIKey | RETPFDTUCPKFEC-UHFFFAOYSA-N |
| SMILES | CC1=CC=CC=C1OCC(CNCCN2C=C(C(=O)NC2=O)C)O |
