For research use only. Not for therapeutic Use.
PRMT5-IN-2 is a rotein arginine methyltransferase 5 (PRMT5) inhibitor extracted from patent WO2018130840A1, compound 3[1].
| Catalog Number | I018283 |
| CAS Number | 1989620-04-3 |
| Synonyms | (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(R)-(4-chloro-3-fluorophenyl)-hydroxymethyl]oxolane-3,4-diol |
| Molecular Formula | C17H16ClFN4O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C17H16ClFN4O4/c18-9-2-1-7(5-10(9)19)11(24)14-12(25)13(26)17(27-14)23-4-3-8-15(20)21-6-22-16(8)23/h1-6,11-14,17,24-26H,(H2,20,21,22)/t11-,12+,13-,14-,17-/m1/s1 |
| InChIKey | GTCYWLXMJRCJNE-QFRSUPTLSA-N |
| SMILES | C1=CC(=C(C=C1C(C2C(C(C(O2)N3C=CC4=C(N=CN=C43)N)O)O)O)F)Cl |
| Reference | [1]. Pedro BELTRAN-ALVAREZ, et al. Arginine methylation inhibitor for treating or preventing cardiovascular disease. WO2018130840A1. |
