PRMT5-IN-20

• CAT Number: I023479
• CAS Number: 880813-30-9
• Molecular Formula: C21H21N3
• Molecular Weight: 315.41
• Purity: ≥95%
• Synonyms: 1-(9-ethylcarbazol-3-yl)-N-(pyridin-3-ylmethyl)methanamine
• InChI: InChI=1S/C21H21N3/c1-2-24-20-8-4-3-7-18(20)19-12-16(9-10-21(19)24)13-23-15-17-6-5-11-22-14-17/h3-12,14,23H,2,13,15H2,1H3
• InChIKey: GAVUWQFIRGBDHN-UHFFFAOYSA-N
• SMILES: CCN1C2=C(C=C(C=C2)CNCC3=CN=CC=C3)C4=CC=CC=C41

PRMT5-IN-20（Cat No.:I023479）is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), an enzyme involved in regulating protein function through methylation of arginine residues. PRMT5 plays a crucial role in various cellular processes, including gene expression, cell cycle regulation, and RNA splicing. By inhibiting PRMT5, PRMT5-IN-20 can disrupt these cellular processes, making it a promising candidate for the treatment of cancers, such as lymphoma and solid tumors, where PRMT5 is often overexpressed. Its targeted action on PRMT5 holds potential for novel therapeutic strategies in oncology and other diseases.