For research use only. Not for therapeutic Use.
Probenecid is a uricosuric agent widely used in research to study gout and hyperuricemia by inhibiting renal tubular reabsorption of uric acid, promoting its excretion. It also inhibits organic anion transporters (OATs), making it a critical tool for investigating drug-drug interactions and renal drug transport mechanisms. Probenecid enhances the efficacy of antibiotics like penicillin by reducing renal clearance, extending their half-life. Its applications span pharmacokinetic studies, renal physiology, and drug development, making it essential for understanding uric acid metabolism and renal transport systems.
| Catalog Number | A000386 |
| CAS Number | 57-66-9 |
| Synonyms | 57-66-9; 4-(Dipropylsulfamoyl)benzoic acid; Probecid; Probenecid acid; Benecid |
| Molecular Formula | C13H19NO4S |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Storage | -20°C |
| IUPAC Name | 4-(dipropylsulfamoyl)benzoic acid |
| InChI | 1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16) |
| InChIKey | DBABZHXKTCFAPX-UHFFFAOYSA-N |
| SMILES | CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(=O)O |
