Probenecid, Water Soluble

• CAT Number: R072071
• CAS Number: 23795-03-1
• Molecular Formula: C13H18NNaO4S
• Molecular Weight: 307.34
• Purity: ≥95%

Probenecid is an inhibitor of organic-anion transporters located in cell membranes. These transporters often extrude fluorescent indicators from cells, and therefore contribute to poor dye retention. This phenomenon usually causes high background in the assays that require the good retention of the dye indicators inside cells. The use of probenecid to inhibit the transporter activity, and thus to reduce leakage of the intracellular dye indicators is a common method for reducing fluorescence background of calcium assays