For research use only. Not for therapeutic Use.
Procyclidine hydrochloride (Cat No.: I001874) is a potent medication with dual properties. Primarily, it functions as an anticholinergic agent, meaning it blocks the action of the neurotransmitter acetylcholine in the nervous system. This property makes it useful in the management of conditions like Parkinson’s disease and drug-induced extrapyramidal symptoms. If you need to, please contact us in time, and we will reply to you as soon as possible within 24 hours.
| Catalog Number | I001874 |
| CAS Number | 1508-76-5 |
| Molecular Formula | C19H30ClNO |
| Purity | ≥95% |
| Target | anti-cholinergic |
| Solubility | 10 mM in H2O |
| Storage | 2-8°C |
| IUPAC Name | 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-ylpropan-1-ol;hydrochloride |
| InChI | InChI=1S/C19H29NO.ClH/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20;/h1,3-4,9-10,18,21H,2,5-8,11-16H2;1H |
| InChIKey | ZFSPFXJSEHCTTR-UHFFFAOYSA-N |
| SMILES | C1CCC(CC1)C(CCN2CCCC2)(C3=CC=CC=C3)O.Cl |
| Reference | </br>1:Syntheses of (S)-(+)-trihexyphenidyl hydrochloride and (S)-(+)-procyclidine hydrochloride, two anticholinergics, using (S)-(-)-3-cyclohexyl-3-hydroxy-3-phenylpropanoic acid as chiral synthon. Schjelderup L, Harbitz O, Groth P, Aasen AJ.Acta Chem Scand B. 1987 May;41(5):356-61. PMID: 3673449 </br>2:Assay of procyclidine hydrochloride, cyclizine hydrochloride and diethylcarbamazine citrate in tablets using ion-responsive electrodes. Campbell MJ, Demetriou B, Jones R.Analyst. 1980 Jun;105(1251):605-11. No abstract available. PMID: 7416480 </br>3:[Poisoning with procyclidine hydrochloride (Kemadrin)]. Meier V.Schweiz Rundsch Med Prax. 1973 Apr 10;62(15):473-5. German. No abstract available. PMID: 4695200 </br>4:The stereochemical basis of anticonvulsant drug action. 3. The structure of procyclidine hydrochloride. Camerman N, Camerman A.Mol Pharmacol. 1971 Jul;7(4):406-12. No abstract available. PMID: 5113235 </br>5:Activation of the EEG by procyclidine hydrochloride in temporal lobe epilepsy. Vas CJ, Exley KA, Parsonage MJ.Epilepsia. 1967 Dec;8(4):241-51. No abstract available. PMID: 5238716 </br>6:EEG activation by procyclidine hydrochloride in temporal lobe epilepsy. Vas CJ, Exley KA, Parsonage MJ.Electroencephalogr Clin Neurophysiol. 1967 Apr;22(4):395. No abstract available. PMID: 4164765 </br>7:[Prophylaxis and therapy of a drug-related Parkinson syndrome with procyclidine hydrochloride (Kemadrin)]. GROSS H, LANGNER E.Wien Klin Wochenschr. 1962 Aug 31;74:569-70. German. No abstract available. PMID: 13902214 </br>8:Effectiveness of procyclidine hydrochloride (kemadrin) and cycrimine hydrochloride (pagitane) in the prevention of airsickness. RENZI AA, MILCH LJ.J Aviat Med. 1958 Aug;29(8):587-9. No abstract available. PMID: 13575361 </br>9:Procyclidine hydrochloride (kemadrin) treatment of parkinsonism; result in 108 patients. ZIER A, DOSHAY LJ.Neurology. 1957 Jul;7(7):485-9. No abstract available. PMID: 13451881 |
