Promen

• CAT Number: I035047
• CAS Number: 2700-47-2
• Molecular Formula: C14H14O2
• Molecular Weight: 214.264
• Purity: 98%
• Synonyms: Promen
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 1-(6-methoxynaphthalen-2-yl)propan-1-one
• InChI: InChI=1S/C14H14O2/c1-3-14(15)12-5-4-11-9-13(16-2)7-6-10(11)8-12/h4-9H,3H2,1-2H3
• InChIKey: LWOTXBQKJLOAOZ-UHFFFAOYSA-N
• SMILES: CCC(c(cc1)cc2c1cc(OC)cc2)=O

Promen (CAT: I035047) is a specialized fluorescent probe renowned for its unique interaction with site II on human serum albumin (HSA). This binding affinity allows Promen to serve as a powerful tool for studying albumin’s behavior and functions in various biochemical and biophysical studies. Its fluorescent properties enable real-time monitoring of albumin-probe interactions, making it a valuable tool for investigating protein-ligand binding mechanisms, drug delivery systems, and protein conformational changes.

Reference

1: González-Jiménez J, Cortijo M. Resonance energy transfer between tryptophan-214 in human serum albumin and acrylodan, prodan, and promen. Protein J. 2004 Jul;23(5):351-5. doi: 10.1023/b:jopc.0000032655.26249.ba. PMID: 15328891.
2: Moreno F, González-Jiménez J. Binding of the Promen fluorescent probe to human serum albumin: a fluorescence spectroscopic study. Chem Biol Interact. 1999 Aug 1;121(3):237-52. doi: 10.1016/s0009-2797(99)00111-8. PMID: 10462056.