Promethazine-d4 hydrochloride

• CAT Number: S000427
• CAS Number: 1173018-74-0
• Molecular Formula: C17H17D4ClN2S
• Molecular Weight: 324.90
• Purity: ≥95%
• IUPAC Name: N,N-dimethyl-1-(1,3,7,9-tetradeuteriophenothiazin-10-yl)propan-2-amine;hydrochloride
• InChI: InChI=1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H/i6D,7D,8D,9D
• InChIKey: XXPDBLUZJRXNNZ-RPMJCVFWSA-N
• SMILES: CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C.Cl

Promethazine-d4 hydrochloride（Cat No.:S000427） is a deuterated form of promethazine, where four hydrogen atoms are replaced with deuterium. This modification enhances the drug’s stability, making it valuable for detailed pharmacokinetic and metabolic studies. Promethazine is an antihistamine used to treat allergy symptoms, nausea, and vomiting, and is often used as a sedative. The hydrochloride salt form increases its solubility and bioavailability. Promethazine-d4 hydrochloride helps researchers understand how deuterium substitution affects the drug’s metabolism and degradation, potentially leading to insights that could improve dosing accuracy and effectiveness in therapeutic applications.