Promethazine Sulfoxide

• CAT Number: R008300
• CAS Number: 7640-51-9
• Molecular Formula: C17H20N2OS
• Molecular Weight: 300.42
• Purity: ≥95%
• Synonyms: N,N,α-Trimethyl-10H-phenothiazine-10-ethanamine 5-Oxide;?N-[2-(Dimethylamino)propyl]phenothiazine S-Oxide; Promethazine 5-Oxide; ?Promethazine 5-Sulfoxide; Romergan Sulfoxide
• Storage: 2-8°C
• IUPAC Name: N,N-dimethyl-1-(5-oxophenothiazin-10-yl)propan-2-amine
• InChI: InChI=1S/C17H20N2OS/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)21(20)17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3
• InChIKey: OWTCLFIFAFHQIX-UHFFFAOYSA-N
• SMILES: CC(CN1C2=CC=CC=C2S(=O)C3=CC=CC=C31)N(C)C

Promethazine sulfoxide（Cat No.:R008300）, is a metabolite of the medication promethazine, which is commonly used as an antihistamine and antiemetic. When promethazine is metabolized in the body, it can be partially converted into promethazine sulfoxide. This sulfoxide form can also exhibit pharmacological activity, contributing to the overall therapeutic effects of promethazine. Promethazine and its metabolites, including promethazine sulfoxide, work by blocking histamine receptors and reducing nausea, vomiting, and allergic reactions. Promethazine sulfoxide’s presence in the body helps extend the medication’s duration of action and influences its efficacy in managing various medical conditions.