For research use only. Not for therapeutic Use.
Propantheline bromide (Cat.No:I003780) is an anticholinergic medication used to treat conditions related to excessive smooth muscle activity, such as irritable bowel syndrome (IBS) and overactive bladder. It works by inhibiting the action of acetylcholine, a neurotransmitter involved in muscle contractions. Propantheline bromide helps relieve symptoms like abdominal pain, cramps, and urinary urgency.
| Catalog Number | I003780 |
| CAS Number | 50-34-0 |
| Molecular Formula | C23H30BrNO3 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | 50 mg/mL in H2O |
| Storage | Store at -20℃ |
| IUPAC Name | methyl-di(propan-2-yl)-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium;bromide |
| InChI | InChI=1S/C23H30NO3.BrH/c1-16(2)24(5,17(3)4)14-15-26-23(25)22-18-10-6-8-12-20(18)27-21-13-9-7-11-19(21)22;/h6-13,16-17,22H,14-15H2,1-5H3;1H/q+1;/p-1 |
| InChIKey | XLBIBBZXLMYSFF-UHFFFAOYSA-M |
| SMILES | CC(C)[N+](C)(CCOC(=O)C1C2=CC=CC=C2OC3=CC=CC=C13)C(C)C.[Br-] |
| Reference | </br>1:[Propantheline bromide is effective against dog drooling]. Gyldenløve M, Thyssen JP.Ugeskr Laeger. 2015 Dec 21;177(52):V67934. Danish. PMID: 26692220 </br>2:Novel strategy for online monitoring of the degradation kinetics of propantheline bromide via a calixarene-based ion-selective electrode. Abd El-Rahman MK, Zaazaa HE, Badr ElDin N, Moustafa AA.Talanta. 2015 Jan;132:52-8. doi: 10.1016/j.talanta.2014.08.068. Epub 2014 Sep 6. PMID: 25476278 </br>3:IR, Raman and SERS spectra of propantheline bromide. Baraldi C, Freguglia G, Tinti A, Sparta M, Alexandrova AN, Gamberini MC.Spectrochim Acta A Mol Biomol Spectrosc. 2013 Feb 15;103:1-10. doi: 10.1016/j.saa.2012.10.070. Epub 2012 Nov 7. PMID: 23228825 </br>4:A stability-indicating proton nuclear magnetic resonance spectroscopic method for the analysis of propantheline bromide in pharmaceutical samples. Hanna GM, Lau-Cam CA.Pharmazie. 2001 Sep;56(9):700-3. PMID: 11593989 </br>5:Reproductive toxicology. Propantheline bromide. [No authors listed]Environ Health Perspect. 1997 Feb;105 Suppl 1:339-40. No abstract available. PMID: 9114352 Free PMC Article</br>6:Clinical efficacy of propantheline bromide in neurocardiogenic syncope: pharmacodynamic implications. Yu JC, Sung RJ.Cardiovasc Drugs Ther. 1997 Jan;10(6):687-92. PMID: 9110111 </br>7:[Allergic contact dermatitis due to propantheline bromide]. Jansen T, Plewig G, Hölzle E.Dtsch Med Wochenschr. 1996 Jan 5;121(1-2):41-2. German. No abstract available. PMID: 8565805 </br>8:Bromide intoxication due to propantheline bromide. Heckerling PS, Ammar KA.Am J Nephrol. 1996;16(6):537-9. PMID: 8955768 </br>9:Propantheline bromide in the management of hyperhidrosis associated with spinal cord injury. Canaday BR, Stanford RH.Ann Pharmacother. 1995 May;29(5):489-92. Review. PMID: 7655132 </br>10:[Determination of chlorphenamine and propantheline bromide in pukeling tablets by differential–linear combination derivative spectrophotometry]. Lin LM, Zhang NJ, Wang HY.Yao Xue Xue Bao. 1991;26(6):451-7. Chinese. PMID: 1789113 |
