Propargyl-PEG1-NHS ester

• CAT Number: I014594
• CAS Number: 1174157-65-3
• Molecular Formula: C10H11NO5
• Molecular Weight: 225.20
• Purity: ≥95%
• Synonyms: Propargyl-PEG1-NHS ester;Propargyl-PEG1-NHS ester
• Target: ADC Linker
• Solubility: Soluble in DMSO
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 3-prop-2-ynoxypropanoate
• InChI: InChI=1S/C10H11NO5/c1-2-6-15-7-5-10(14)16-11-8(12)3-4-9(11)13/h1H,3-7H2
• InChIKey: WKIKHHMUNOVQLD-UHFFFAOYSA-N
• SMILES: C#CCOCCC(=O)ON1C(=O)CCC1=O

Propargyl-PEG1-NHS ester（Cat No.:I014594）is a chemical compound commonly used in bioconjugation and drug delivery applications. It consists of a polyethylene glycol (PEG) linker with a propargyl group at one end and an NHS (N-hydroxysuccinimide) ester at the other. The NHS ester reacts with primary amines, enabling the attachment of biomolecules, such as proteins or peptides, to the PEG linker. This conjugation enhances solubility, stability, and bioavailability of the attached molecules. It is particularly useful in the development of targeted therapies, diagnostic agents, and in the preparation of novel biomaterial-based systems.