For research use only. Not for therapeutic Use.
Propargyl-PEG12-bromide（Cat No.:I016225）is a versatile compound commonly used in bioconjugation and chemical biology applications. It consists of a propargyl group (a terminal alkyne), a polyethylene glycol (PEG) linker with twelve ethylene glycol units (PEG12), and a bromide group. The propargyl group allows for click chemistry reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling efficient conjugation with azide-functionalized molecules. The PEG12 linker enhances solubility and stability, making it useful in drug delivery systems, protein labeling, and biomolecule modification. This compound is widely used for creating stable conjugates in research, particularly in targeted therapies.
| Catalog Number | I016225 |
| CAS Number | 2410937-34-5 |
| Molecular Formula | C₂₉H₅₅BrO₁₃ |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]prop-1-yne |
| InChI | InChI=1S/C29H55BrO13/c1-2-4-31-6-8-33-10-12-35-14-16-37-18-20-39-22-24-41-26-28-43-29-27-42-25-23-40-21-19-38-17-15-36-13-11-34-9-7-32-5-3-30/h1H,3-29H2 |
| InChIKey | CKLGLALHALJBDM-UHFFFAOYSA-N |
| SMILES | C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCBr |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
