Propargyl-PEG2-NHBoc

• CAT Number: I017184
• CAS Number: 869310-84-9
• Molecular Formula: C₁₂H₂₁NO₄
• Molecular Weight: 243.3
• Purity: ≥95%
• Target: PROTAC
• IUPAC Name: tert-butyl N-[2-(2-prop-2-ynoxyethoxy)ethyl]carbamate
• InChI: InChI=1S/C12H21NO4/c1-5-7-15-9-10-16-8-6-13-11(14)17-12(2,3)4/h1H,6-10H2,2-4H3,(H,13,14)
• InChIKey: WBOOWEAGRWGHMV-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NCCOCCOCC#C

Propargyl-PEG2-NHBoc (Cat No.:I017184) is a chemical compound used in organic synthesis and drug delivery applications. It consists of a polyethylene glycol (PEG) chain with two ethylene glycol units (PEG2), a propargyl group, and a tert-butoxycarbonyl (Boc) protecting group. The propargyl group allows for conjugation reactions, while the PEG chain provides solubility and biocompatibility. The Boc protecting group safeguards the amine functionality during synthesis. Propargyl-PEG2-NHBoc is commonly employed in the preparation of functionalized polymers, bioconjugates, and drug delivery systems, enabling the attachment of various molecules to the PEG backbone through click chemistry reactions.

Reference

[1]. Nello Mainolfi, et al. rak degraders and uses thereof. US20190192668A1.