Propargyl-PEG3-NHS ester

• CAT Number: I014607
• CAS Number: 1428629-71-3
• Molecular Formula: C14H19NO7
• Molecular Weight: 313.31
• Purity: ≥95%
• Synonyms: Propargyl-PEG3-NHS ester;Propargyl-PEG3-NHS ester
• Target: PROTAC
• Solubility: Soluble in DMSO
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 3-[2-(2-prop-2-ynoxyethoxy)ethoxy]propanoate
• InChI: InChI=1S/C10H15O5.C4H4NO2/c1-2-4-13-6-8-15-9-7-14-5-3-10(11)12;6-3-1-2-4(7)5-3/h1H,3-9H2;1-2H2
• InChIKey: AFNLQDMYYPMSFL-UHFFFAOYSA-N
• SMILES: C#CCOCCOCCOCCC(=O)ON1C(=O)CCC1=O

Propargyl-PEG3-NHS Ester(CAT: I014607) is a versatile bioconjugation reagent widely employed in chemical biology and drug development research. This compound features a propargyl group for copper-catalyzed azide-alkyne cycloaddition (CuAAC, or “click chemistry”) and an NHS ester for efficient coupling with primary amines in biomolecules such as proteins, peptides, and antibodies. The PEG3 spacer enhances water solubility and reduces steric hindrance, facilitating efficient conjugation reactions. Propargyl-PEG3-NHS Ester is ideal for applications including probe labeling, targeted drug delivery, and the synthesis of functionalized biomaterials. Its high purity and stability make it a reliable tool for precise and reproducible bioconjugation experiments.