Propargyl-PEG4-Maleimide

• CAT Number: I014618
• CAS Number: 1609651-90-2
• Molecular Formula: C18H26N2O7
• Molecular Weight: 382.41
• Purity: ≥95%
• Synonyms: Propargyl-PEG4-Maleimide;Propargyl-PEG4-Maleimide
• Target: PROTAC Linkers
• Solubility: Soluble in DMSO
• IUPAC Name: 3-(2,5-dioxopyrrol-1-yl)-N-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethyl]propanamide
• InChI: InChI=1S/C18H26N2O7/c1-2-8-24-10-12-26-14-15-27-13-11-25-9-6-19-16(21)5-7-20-17(22)3-4-18(20)23/h1,3-4H,5-15H2,(H,19,21)
• InChIKey: GHEBECZRHJXPTL-UHFFFAOYSA-N
• SMILES: C#CCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O

Propargyl-PEG4-Maleimide（Cat No.:I014618）is a chemical compound that consists of a propargyl group, a polyethylene glycol (PEG) linker with four ethylene glycol units, and a maleimide group. The propargyl group enables the compound to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, a form of click chemistry, while the maleimide group is highly reactive with thiol groups, making it useful for conjugating molecules in bioconjugation and drug delivery applications. The PEG4 linker provides solubility, stability, and flexibility, making Propargyl-PEG4-Maleimide useful in the synthesis of targeted therapeutics, diagnostic agents, and biomolecule conjugates in biomedical research.