Propargyl-PEG4-NHS ester

• CAT Number: I014621
• CAS Number: 1428629-70-2
• Molecular Formula: C16H23NO8
• Molecular Weight: 357.36
• Purity: ≥95%
• Synonyms: Propargyl-PEG4-NHS ester;Propargyl-PEG4-NHS ester
• Target: ADC Linker
• Solubility: Soluble in DMSO
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C12H19O6.C4H4NO2/c1-2-4-15-6-8-17-10-11-18-9-7-16-5-3-12(13)14;6-3-1-2-4(7)5-3/h1H,3-11H2;1-2H2
• InChIKey: WMBISYJCYQJEQK-UHFFFAOYSA-N
• SMILES: [O]C(CCOCCOCCOCCOCC#C)=O.O=C1[N]C(CC1)=O

Propargyl-PEG4-NHS Ester(CAT: I014621) is a reactive chemical linker commonly used in bioconjugation and click chemistry applications. It features a propargyl group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions and an N-hydroxysuccinimide (NHS) ester for efficient amine-reactive conjugation. The PEG4 spacer enhances solubility and flexibility, reducing steric hindrance in conjugated biomolecules. Propargyl-PEG4-NHS Ester is widely used in chemical biology and drug delivery research, supporting the development of targeted therapeutics, imaging probes, and biomolecule labeling. Its versatility and reliability make it a critical tool for advanced bioconjugation techniques in diverse experimental and therapeutic contexts.