Propargyl-PEG5-NHS ester

• CAT Number: I014632
• CAS Number: 1393330-40-9
• Molecular Formula: C18H27NO9
• Molecular Weight: 401.41
• Purity: ≥95%
• Synonyms: Propargyl-PEG5-NHS ester;Propargyl-PEG5-NHS ester
• Target: PROTAC
• Solubility: Soluble in DMSO
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C18H27NO9/c1-2-6-23-8-10-25-12-14-27-15-13-26-11-9-24-7-5-18(22)28-19-16(20)3-4-17(19)21/h1H,3-15H2
• InChIKey: ACZDUKRWTPZVRP-UHFFFAOYSA-N
• SMILES: C#CCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O

Propargyl-PEG5-NHS ester（Cat No.:I014632）is a chemical compound commonly used in bioconjugation and drug delivery applications. It features a polyethylene glycol (PEG) linker with a propargyl group at one end and an NHS (N-hydroxysuccinimide) ester at the other. The NHS ester reacts with primary amines, facilitating the conjugation of biomolecules like proteins or peptides to the PEG linker. This modification improves solubility, stability, and bioavailability of the conjugated molecules. It is especially useful in creating targeted therapies, diagnostic agents, and novel biomaterial systems, where the PEG chain provides flexibility and enhanced circulation time in vivo.